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Index > Protein center > WNT10A(Gene name) > Human
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  • WNT10A (Gene name),
  • Protein Wnt-10a (Protein name ),  WN10A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    WNT10A;
    Protein name:
    Protein Wnt-10a;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    417
    Sequence:
    50:
    MGSAHPRPWL | RLRPQPQPRP | ALWVLLFFLL | LLAAAMPRSA | PNDILDLRLP | 
    100:
    PEPVLNANTV | CLTLPGLSRR | QMEVCVRHPD | VAASAIQGIQ | IAIHECQHQF | 
    150:
    RDQRWNCSSL | ETRNKIPYES | PIFSRGFRES | AFAYAIAAAG | VVHAVSNACA | 
    200:
    LGKLKACGCD | ASRRGDEEAF | RRKLHRLQLD | ALQRGKGLSH | GVPEHPALPT | 
    250:
    ASPGLQDSWE | WGGCSPDMGF | GERFSKDFLD | SREPHRDIHA | RMRLHNNRVG | 
    300:
    RQAVMENMRR | KCKCHGTSGS | CQLKTCWQVT | PEFRTVGALL | RSRFHRATLI | 
    350:
    RPHNRNGGQL | EPGPAGAPSP | APGAPGPRRR | ASPADLVYFE | KSPDFCEREP | 
    400:
    RLDSAGTVGR | LCNKSSAGSD | GCGSMCCGRG | HNILRQTRSE | RCHCRFHWCC | 
    417:
    FVVCEECRIT | EWVSVCK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    SMR:
    MIM:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein Wnt-10a
    Cat.:
    E5239h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Protein Wnt-10a
    Cat.:
    E5239m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Protein Wnt-10a
    Cat.:
    U5239h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Protein Wnt-10a
    Cat.:
    U5239m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Protein Wnt-10a
    Cat.:
    P5239Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Protein Wnt-10a
    Cat.:
    P5239Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Protein Wnt-10a
    Monoclonal Antibody for Human Protein Wnt-10a
    Protein for Human Protein Wnt-10a
    Protein for Human Protein Wnt-10a

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning and characterization of six novel human WNT genes."
      Testa T.T. , Mossakowska D.E. , Carter P.S. , Hu E. , Zhu Y. , Kelsell D.P. , Murdock P.R. , Herrity N.C. , Lewis C.J. , Cross D.A. , Culbert A.A. , Reith A.D. , Barnes M.R.
      Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Genomic sequence of the Wnt6 gene and the Wnt10a gene from human 2q35."
      Rump A. , Hayes C. , Brown S.D.M. , Rosenthal A.
      Submitted (2000-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly co-expressed in SW480 cells."
      Kirikoshi H. , Sekihara H. , Katoh M.
      Biochem. Biophys. Res. Commun.283:798-805(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
      tissue: Thymus.
    5. 5.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    8. 8.
      "Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia."
      Adaimy L. , Chouery E. , Megarbane H. , Mroueh S. , Delague V. , Nicolas E. , Belguith H. , de Mazancourt P. , Megarbane A.
      Am. J. Hum. Genet.81:821-828(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN OODD
    9. 9.
      "WNT10A mutations are a frequent cause of a broad spectrum of ectodermal dysplasias with sex-biased manifestation pattern in heterozygotes."
      Bohring A. , Stamm T. , Spaich C. , Haase C. , Spree K. , Hehr U. , Hoffmann M. , Ledig S. , Sel S. , Wieacker P. , Ropke A.
      Am. J. Hum. Genet.85:97-105(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS OODD GLN-128 AND ILE-228;INVOLVEMENT IN SSPS
    10. 10.
      "Only four genes (EDA1, EDAR, EDARADD, and WNT10A) account for 90% of hypohidrotic/anhidrotic ectodermal dysplasia cases."
      Cluzeau C. , Hadj-Rabia S. , Jambou M. , Mansour S. , Guigue P. , Masmoudi S. , Bal E. , Chassaing N. , Vincent M.C. , Viot G. , Clauss F. , Maniere M.C. , Toupenay S. , Le Merrer M. , Lyonnet S. , Cormier-Daire V. , Amiel J. , Faivre L. , more...
      Hum. Mutat.32:70-72(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN HYPOHIDROTIC/ANHIDROTIC ECTODERMAL DYSPLASIA;VARIANTS TYR-143; MET-145; ILE-228 AND CYS-360
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS STHAG4 ASN-217 AND ILE-228
    12. 12.
      "Mutations in WNT10A are present in more than half of isolated hypodontia cases."
      van den Boogaard M.J. , Creton M. , Bronkhorst Y. , van der Hout A. , Hennekam E. , Lindhout D. , Cune M. , Ploos van Amstel H.K.
      J. Med. Genet.49:327-331(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS STHAG4 LYS-95 AND GLN-128;VARIANTS MET-145; TRP-163; CYS-277 AND LYS-306
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